The continuing adventures of paranormal investigators Dr. Peter Venkman, Dr. Egon Spengler, Dr. Ray Stantz, Winston Zeddemore, their secretary Janine Melnitz and their mascot ghost Slimer.
Peter's father shows up with a map to the lost treasure deep in the jungles of Mexico. Ray and Slimer agree to aid him, but the three hunters get more than they bargained for when they face the Winged Spirits guarding the treasure!
Slimer has been pestering they guys too much and they finally snap at him. He sulks off to the attic, just as the Ghostbusters are called out on a mission. When a powerful ghost heads for the firehouse to destroy it, a despondent Slimer is the last line of defense!
The Ghostbusters are called to Japan to investigate the sighting of several immense creatures in the Tokyo Bay. A local schoolboy, Kenji, tells the Ghostbusters that the creatures are identical to old Japanese movie monsters of the fifties!
As a man who hates bugs, Peter is horrified with an ant farm arrives in the mail for Ray. Peter's phobia is put to the test when he is taken captive by the spirit of the long-dead Egyptian Insect God, Apshai, and his horde of giant insect slaves.